Stein Ove Danielsen has tested a telephone-based follow-up intervention to see if it reduces the high short-term readmission rates following aortic valve replacement.


  1. 30-day readmissions following aortic valve replacement is high.
  2. A telephone-based follow-up does not reduce 30-day readmission after aortic valve implantation.
  3. Anixiety symptoms are reduced with structured telephone follow-up after aortic valve replacement.


Thesis: Optimising patient discharge and follow-up after surgical aortic valve replacement to reduce readmissions and improve patient-reported outcomes
Candidate: Stein Ove Danielsen
Time: June 18, 2020 at 10:15
Place: Online-based solution, due to the covid-19 situation
Link to university website


(1) A meta-analysis performed by Danielsen and colleagues shows that 17% are readmitted to hospital within 30 days of aortic valve surgery. Following TAVI the readmission rate is 16%. The review includes results from 32 articles with a total of more than 500,000 patients.

The most frequent causes of rehospitalization are heart failure, arrhythmia, infection and respiratory problems. No risk factors for readmission following surgery were found, whereas patients with diabetes, chronic lung disease, atrial fibrillation and kidney problems are at increased risk of readmission following TAVI.

(2) Structured telephone follow-up and a 24/7 hotline did not reduce 30-day all-cause readmissions following aortic surgery. 288 patients were included in the randomized controlled trial that compared the telephone-based follow-up intervention with usual care.

22.3% of the patients were readmitted during follow-up, and patients with anxiety symptoms and pleural drainage before discharge were at increased risk. The intervention reduced symptoms of anxiety, but depression and participant-reported health state were unaffected.

(3) More than half of the patients in the randomized controlled study reported to be satisfied with the telephone intervention and almost everyone felt safe.


(1) Danielsen, S. O., Moons, P., Sandven, I., Leegaard, M., Solheim, S., Tønnessen, T., & Lie, I. (2018). Thirty-day readmissions in surgical and transcatheter aortic valve replacement: a systematic review and meta-analysisInternational journal of cardiology268, 85-91.

(2) Danielsen, S. O., Moons, P., Sandvik, L., Leegaard, M., Solheim, S., Tønnessen, T., & Lie, I. (2020). Impact of telephone follow-up and 24/7 hotline on 30-day readmission rates following aortic valve replacement-a randomized controlled trial. International Journal of Cardiology300, 66-72.

(3) Danielsen, S. O., Moons, P., Leegaard, M., Solheim, S., Tønnessen, T., & Lie, I. (2020). Facilitators of and barriers to reducing thirty-day readmissions and improving patient-reported outcomes after surgical aortic valve replacement: a process evaluation of the AVRre trialBMC health services research20, 1-11.

Latest News

May 28, 2024

Photos from the workshop on Advancing Ischemic Heart Disease Research

Approximately 25 researchers met in Trondheim for the new workshop called “Advancing Ischemic Heart Disease…

Read more
May 14, 2024

Photos from Course in Cardiac Mechanics 2024

Cardiac researchers and clinical cardiologists need to know key concepts and terms for measuring and describing…

Read more
April 28, 2024

Professor Kristina H. Haugaa receives the 2024 Heart Research Award

The Norwegian Health Association has awarded the prestigious 2024 Heart Research Award (Hjerteforskningsprisen) to professor Kristina…

Read more
September 08, 2023

Annual Symposium 2023: Winners and photos

More than 100 participants attended the 21st Annual Norwegian Symposium on Heart Research, hosted by…

Read more
Norheart uses cookies for analytical purposes, content and ads customisation, and to further develop our services.
Learn more
Show again