The main theme for Rannveig Sakshaug Eldholm‘s PhD thesis is the impact of vascular comorbidities on disease progression and clinical profile in Alzheimer’s disease.


MAIN RESULTS:

  1. Cardiovascular risk factors are prevalent in Alzheimer’s disease
  2. Cardiovascular risk factors do not impact progression in Alzheimer’s disease.

THESIS DEFENCE:

Thesis: Alzheimer’s Disease – The Impact of Vascular Comorbidity on Disease Progression and Clinical Profile
Candidate: Rannveig Sakshaug Eldholm
Time: March 21, 2019 at 12:15
Place: St. Olavs Hospital, Medical Technical Research Center: Auditorium MTA
Link to university website (in Norwegian)


SUMMARY:

(2) Among 282 Alzheimer’s disease patients, 83 % had hypertension, 53 % hypercholesterolemia, 41 % were overweight, 10 % were smokers and 9 % had diabetes. The cardiovascular risk factors, however, did not associate with Alzheimer’s disease progression over the next two years. The study includes patients from three Norwegian memory clinics.

(1/3) One of the other articles in the thesis show that cognitive test results at baseline are predictors of progression rate, and that progression rate varies considerable among patients with Alzheimer’s disease. Eldholm and co-workers also found no difference in disease symptoms between Alzheimer’s disease patients with and without cerebrovascular disease.


REFERENCES:

(1) Eldholm, R. S., Barca, M. L., Persson, K., Knapskog, A. B., Kersten, H., Engedal, K., Selbæk, G., Brækhus, A:, Skovlund, E., & Saltvedt, I. (2018). Progression of Alzheimer’s disease: a longitudinal study in Norwegian memory clinicsJournal of Alzheimer’s Disease, (Preprint), 1-12.

(2) Eldholm, R. S., Persson, K., Barca, M. L., Knapskog, A. B., Cavallin, L., Engedal, K., .Selbæk, G., Skovlund, E., & Saltvedt, I. (2018). Association between vascular comorbidity and progression of Alzheimer’s disease: a two-year observational study in Norwegian memory clinics. BMC geriatrics18(1), 120.

Latest News

April 28, 2024

Professor Kristina H. Haugaa receives the 2024 Heart Research Award

The Norwegian Health Association has awarded the prestigious 2024 Heart Research Award (Hjerteforskningsprisen) to professor Kristina…

Read more
September 08, 2023

Annual Symposium 2023: Winners and photos

More than 100 participants attended the 21st Annual Norwegian Symposium on Heart Research, hosted by…

Read more
April 30, 2023

Professor Dan Atar receives the 2023 Heart Research Award

The Norwegian Health Association has awarded the prestigious 2023 Heart Research Award (Hjerteforskningsprisen) to professor Dan…

Read more
October 31, 2022

Pictures from Introductory Course to Cardiovascular Research and Medicine 2022

23 students completed NORHEART’s Introductory Course to Cardiovascular Research and Medicine in Oslo 17–21 October. As usual,…

Read more
Norheart uses cookies for analytical purposes, content and ads customisation, and to further develop our services.
Accept
Learn more
Show again