Recurrence of stroke more than doubles mortality

Andrej Netland Khanevski has looked at the rates of re-admittance to hospital due to recurrent strokes, transient ischemic attacks (TIA) and stroke mimics.


MAIN RESULTS:

  1. Short- and long-term rates of clinical recurrent events after inciden
  2. Stroke mimics is more common reason for re-admittance than actual recurrent stroke.
  3. New admittance after stroke is associated with doubled mortality.

THESIS DEFENCE:

Thesis: Clinical recurrent events after incident stroke or transient ischemic attack
Candidate: Andrej Netland Khanevski
Time: June 26, 2020 at 12:15
Place: Online-based solution, due to the covid-19 situation
Link to university website (in Norwegian)


SUMMARY:

Almost 2000 patients admitted with ischemic stroke or TIA at Haukeland University Hospital between 2007 and 2013 are included in Khanevksi’s studies.

(1) Nearly 2% were admitted with a new stroke/TIA within a month of the first event. The risk was higher in patients with large strokes caused by atherosclerosis, as well as in patients with cancer.

(2) The recurrence rates were 5% and 11% at one and five years, respectively. At the end of follow-up in 2016, 14% of the patients had been re-admitted. Older patients with hypertension and prior stroke were at higher risk of new hospitalizations in the long term.

36% of the patients died during follow-up. All-cause mortality was more than doubled in patients who experienced recurrent events.

(3) Stroke mimics were more frequent than recurrent strokes/TIAs, occuring in 19% of the patients during the full follow-up period. The risk was highest the first year after the initial event. Mimics were associated with symptoms such as infections, seizures, dizziness, migraine and syncopes.


REFERENCES:

(1) Khanevski, A. N., Bjerkreim, A. T., Novotny, V., Næss, H., Thomassen, L., Logallo, N., & Kvistad, C. E. (2018). Thirty‐Day Recurrence After Ischemic Stroke Or TIABrain and Behavior, e01108.

(2) Khanevski, A. N., Bjerkreim, A. T., Novotny, V., Næss, H., Thomassen, L., Logallo, N., & Kvistad, C. E. (2019) Recurrent ischemic stroke: incidence, predictors and impact on mortality Acta Neurologica Scandinavica

(3) Khanevski, A. N., Kvistad, C. E., Novotny, V., Næss, H., Thomassen, L., Logallo, N., & Bjerkreim, A. T. (2019). Incidence and Etiologies of Stroke Mimics After Incident Stroke or Transient Ischemic AttackStroke50(10), 2937-2940.

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