Subarachnoid hemorrhage results from a ruptured intracranial aneurysm. The PhD thesis of Torbjørn Øgard Skodvin can make it easier to identify patients that need brain surgery.

MAIN RESULTS:

1. Postrupture morphology could be inaccurate to evaluate the rupture risk of intact intracranial aneurysms.
2. Hemodynamics at the time of diagnosis could be early predictors of rupture.
3. The prerupture morphology of an aneurysm could be of value when assessing rupture risk.

THESIS DEFENCE:

Thesis: Predicting rupture of intracranial aneurysms: morphological and hemodynamic parameters
Candidate: Torbjørn Øgard Skodvin
Time: April 27, 2018 at 12:15
Place: UiT The Arctic University of Norway: MH-building, Auditorium 7
Link to university website (in Norwegian)

SUMMARY:

(1) Using postrupture morphology to predict rupture risk of an intracranial aneurysm is inaccurate because of morphological changes at the time of rupture. By comparing pre- and postrupture angiograms from 29 patients, Skodvin and colleagues found that almost all one-dimensional parameter medians were significantly larger after rupture. They conclude that aneurysm morphology changes both as a result of time and the rupture per se.

REFERENCES:

(1) Skodvin, T. Ø., Johnsen, L. H., Gjertsen, Ø., Isaksen, J. G., & Sorteberg, A. (2017). Cerebral aneurysm morphology before and after rupture: nationwide case series of 29 aneurysms. Stroke, 48(4), 880-886.

(2) Skodvin, T. Ø., Evju, Ø., Helland, C. A., & Isaksen, J. G. (2017). Rupture prediction of intracranial aneurysms: a nationwide matched case-control study of hemodynamics at the time of diagnosis. Journal of neurosurgery, 1-7.

(2) Skodvin, T. Ø., Evju, Ø., Sorteberg, A., & Isaksen, J. G. (2018). Prerupture Intracranial Aneurysm Morphology in Predicting Risk of Rupture: A Matched Case-Control Study. Neurosurgery.